In contrast, the mean level of high sensitivity C-reactive protein was not significantly different. There was no statistically significant difference in the levels of ANP and N-terminal probrain natriuretic peptide (NT-proBNP), Vorinostat clinical according to the diurnal BP pattern. There were no differences between the groups in the office, 24-hr average and daytime BP values. However, Inhibitors,research,lifescience,medical both systolic and diastolic BP values were significantly increased in the non-dippers group, during both NSC 737664 nocturnal and awakening time. Table 1 Clinical characteristics and blood pressure of patients with dipper

and non-dipper type of hypertension Conventional and volumetric echocardiography parameters Conventional echocardiographic parameters were presented in Table 2. LV dimension, wall thickness and mass index were not significantly different between the two investigated groups. There were also no significant differences in the systolic and diastolic LV functions, according to the diurnal BP pattern. Table 2 Conventional Inhibitors,research,lifescience,medical echocardiographic parameters according to the diurnal blood pressure fluctuation LA phasic volumes and other parameters representing the LA function were shown in Table 3. LA maximal volume and LA volume at the onset of the atrial systole were significantly increased in the non-dipper group. Although there was no Inhibitors,research,lifescience,medical difference in both LA passive emptying volume and fraction between

the two groups, the LA expansion Inhibitors,research,lifescience,medical index, LA active emptying volume and LA active emptying fraction were significantly increased in the non-dippers group. In contrast, the LA conduit volume was increased in the dippers group (dippers = 21.43 ± 6.51 mL/m2 vs non-dippers = 17.05 ± 5.80 mL/m2, p = 0.03). Table 3 Left atrial phasic volumetric parameters and Inhibitors,research,lifescience,medical atrial fraction in the dipper and non-dipper groups LA strain and strain rate according to the diurnal BP variation Table 4 shows the peak strain value of the LA measured during the reservoir period. Although there was no significant difference between the groups in the segmentally evaluated values, the averaged values showed that the peak strain of the LA was

significantly increased in the non-dippers group (dippers = 21.26 ± 4.23% vs non-dippers Anacetrapib = 24.91 ± 5.20%, p = 0.02). The strain rates of the LA were also significantly different between dippers and non-dippers. Thus, the strain rates measured during the reservoir and contractile periods showed differences between the groups. In contrast, the difference in strain rate measured during the conduit period was not statistically significant between the two groups (Table 4). When comparing the natriuretic peptide levels and the deformation parameters, we found only weak relationship between the values of the strain measured at the septum and the serum value of ANP. Table 4 Peak strain and strain rate of the left atrium Reliability Bland-Altman plots were demonstrated in Fig. 2.