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selleck chemicals llc 38. Fagnocchi L, Biolchi A, Ferlicca F, Boccadifuoco G, Brunelli B, Brier S, Norais N, Chiarot E, Bensi G, Kroll JS, Pizza M, Donnelly J, Giuliani MM, Delany I: Transcriptional Regulation of the nadA Gene in Neisseria meningitidis Impacts the Prediction of Coverage of a Multicomponent Meningococcal Serogroup B Vaccine. Infect Immun 2013,81(2):560–569.PubMedCentralPubMedCrossRef Authors’ contributions GT, MT, MP participated in the study design and the preparation of the manuscript, EH, KK, AX participated in the laboratory experimental work and in the interpretation of data, SB, AM, LO and MC participated in the analysis Rucaparib supplier of the data.”
“Background Mycoplasmas are the smallest known self-replicating prokaryotes originally isolated from bovine pleuropneumonia and are

also referred as pleuropneumonia like organisms (PPLO). A key characteristic of mycoplasma is the lack of a cell wall, which allows exchange of different components between the host membrane and the M. pneumoniae membrane after adhesion [1, 2]. M. pneumoniae is a human pathogen that colonizes the ciliated upper and lower respiratory tract, causing atypical pneumonia. M. pneumoniae is also found to be associated with other respiratory tract infections such as tracheobronchitis, bronchiolitis, croup, Acute Respiratory Distress Syndrome (ARDS), Guillain-Barre Syndrome (GBS), stroke and less severe upper respiratory tract infections in older children as well as in young adults [3–7]. Adherence of M. pneumoniae to the human host respiratory epithelium is a prerequisite for the colonization and AZD3965 subsequent induction of disease [4, 8]. It attaches to ciliated epithelial cells in the respiratory tract, where it induces ciliostasis that protects the M.