Malnutrition is characterized by depletion of visceral protein stores, gastrointestinal malabsorbtion, negative energy balance, and gastrointestinal (GI)symptoms. The aim of this study is to evaluate the nutritional status of ICU inpatients receiving nutritional support by focusing on GI symptoms. Methods: A cross sectional study was conducted to collect data on 100 adult patients who

admitted to ICU ward within 3 months and had a hospital stay of 5 days or more. Data on GI symptoms, anthropometric indices and biochemical markers of nutritional status were collected. Relationships between malnutrition and above-mentioned variables were determined. Patients DNA Synthesis inhibitor click here were classed into three nutritional status groups according to albumin and ideal body weight (IBW): I: weight > 90% IBW, II: weight 76–90% IBW, III: weight 60–75% IBW. Results: Overall, 68% were corresponding to group I, 27% to group II and the others in group III. Albumin (1.4 ± 0.54, 1 and 2 g/dl in groups I, II and III respectively)

and total protein levels (5.1 ± 0.75, 4.5 ± 1.48 and 5 g/dl in groups I, II and III respectively) were significantly associated with malnutrition in all groups (p < 0.05). Patients in second group had more GI symptoms rather than patients whose body weight was more than 90% of IBW (50% v. s 41.7%). No significant association

between anthropometric indices and malnutrition was observed. Conclusion: High prevalence of malnutrition among ICU inpatients regarding gastrointestinal disorders caution to provide a nutritional health care team including gastrointestinal professionals medchemexpress and dietitians who evaluate the effectiveness of treatment and supplementations. Key Word(s): 1. gasterointestine; 2. ICU; 3. Nutrition; 4. assessment; Presenting Author: ZHAO XIAODI Additional Authors: LU YUANYUAN, FAN DAIMING Corresponding Author: FAN DAIMING Affiliations: the Fourth Military Medical University Objective: BACKGROUND/AIMS: Proliferation and metastasis are major clinical obstacles in the treatment of gastric cancer (GC). MicroRNAs have been emerged as regulators in carcinogenesis through acting on multiple oncogenes and tumor suppressors. Our previously studies demonstrated aberrant miR-7 expression affects tumor migration and invasion in gastric cancer. In this study, we investigated the biological roles and the underlying mechanisms of miR-7 in GC proliferation. Methods: METHODS: The expression of miR-7 in GC cell lines and tissues was detected by qRT-PCR.