Helicobacter pylori seroprevalence rates were calculated to have decreased from 36% to 14% in pilot study, from 12% to 4% among subjects invited in 1996, from 3% to 2% among subjects aged 15 and from 27% to 12% among subjects aged 45 in 1997–2000. An epidemiologic questionnaire in 1996 revealed that crowding in the childhood household, low education of the mother, current smoking and alcohol consumption, unfavorable housing conditions, and sick leaves due to dyspepsia were independently associated with H. pylori infection. Conclusions: This intervention with high participation rates resulted in a significant decline in calculated H. pylori seroprevalence rates.
see more Although the low prevalence of H. pylori infection may limit the cost efficiency of the program, the intervention is expected to reduce the burden of H. pylori-associated diseases. “
“Several
epidemiological studies proposed an association between Helicobacter pylori ( H. pylori) infection with insulin resistance (IR) and metabolic syndrome (MetS). However, up to date there is no conclusive evidence regarding this association. To investigate the prevalence and correlates of H. pylori infection among Lebanese adults and to evaluate its association with IR and MetS. Stored blood samples of adults Opaganib participating in the national Nutrition and Non-Communicable Diseases Risk factors survey conducted in Lebanon were used for this study (n = 308). H. pylori-specific immunoglobulin G antibody titers were measured by ELISA. Data available included, in addition
to anthropometric measurements, sociodemographic and lifestyle characteristics, blood pressure, and biochemical indices (serum selleck insulin, HDL, LDL, TAG, glucose). A HOMA –IR level was used to assess insulin resistance. The International Diabetes Federation criteria were used to classify study participants with MetS. The prevalence of H. pylori infection in the study sample was 52% (95% CI, 46.43–57.57). A higher crowding index was associated with a 50% increase in the odds of infection (OR, 1.41; CI, 1.08–2.27). Blood pressure, waist circumference, serum HDL, LDL, TAG, and glucose levels were comparable between H. pylori positive and negative subjects. The odds of IR and MetS were not significantly different between the two groups. Prevalence of H. pylori infection in Lebanon is comparable to other developing countries. Furthermore, our findings suggested no association of H. pylori infection with IR or MetS. Eradication of H. pylori infection to prevent IR or MetS is not warranted. “
“Background: The prevalence of Helicobacter pylori has declined over recent decades in developed countries. The increasing prevalence with age is largely because of a birth cohort effect. We previously observed a decline in H. pylori prevalence in 6- to 8-year-old Dutch children from 19% in 1978 to 9% in 1993. Knowledge about birth-cohort-related H.