MethodsAn initial sample of 154 dyads was recruited, and distress questionnaires

(Hospital Anxiety and Depression Scale, Symptom Checklist 9-Item Short Version and 12-Item Short Form Health Survey) were assessed over four time points. Linear mixed models and actor-partner interdependence models were applied.

ResultsA significant proportion of patients and their partners (up to 40%) reported high levels of anxiety, depression, psychological distress, and low quality of life over the course of the investigation. Mixed model analyses revealed that higher risks for clinical relevant anxiety and depression in couples exist for female patients and especially for female partners. Tipifarnib mouse Although psychological strain decreased over time, the risk for elevated distress in female partners remained. Modeling patient-partner interdependence over time

stratified by patients’ gender revealed specific effects: a moderate correlation between distress in patients and partners, and a transmission of distress from male patients to their female partners.

ConclusionsOur findings provide empirical support for gender-specific transmission of distress in dyads coping with cancer. This should be considered as an important starting point for planning systemic psycho-oncological interventions and conceptualizing further research. Copyright (c) 2013 John Wiley & Sons, Ltd.”
“Placental mesenchymal dysplasia Quizartinib purchase is a rare condition characterized by enlarged multicystic placenta with anechoic regions on ultrasound. Gross examination shows grapelike vesicles which mimics molar pregnancy. Microscopic findings shows large edematous villi with cistern formation interspersed with normal villi. The absence of trophoblastic proliferation and trophobastic inclusions differentiates it from molar pregnancy. We report a new case of placental mesenchymal dysplasia. A 31-year-old G2P1 presented with preterm vaginal bleeding at 24 5/7 weeks of gestation. Ultrasound findings show cystic placenta and placenta previa. She

went into preterm labor and delivered a female baby with no dysmorphic features but later suffered from complications of prematurity. Selleckchem GSK461364 Pathologically, the placenta showed multiple grapelike cystic vesicles with unremarkable chorionic vessels. Microscopically, enlarged edematous villi with cistern formation were noted. Trophoblastic proliferation or inclusions were not seen.”
“Well-defined poly(dimethylsiloxane-b-styrene) diblock copolymers were prepared by reversible addition fragmentation chain-transfer (RAFT) polymerization. Monohydroxyl-terminated polydimethylsiloxane was modified to form a functional polydimethylsiloxane/macro-RAFT agent, which was reacted with styrene to form the diblock copolymers.